I also tried running the release version, and as I expected it performed better than the debug version under the profiler, so the universe was still in its place, but still, I would very much like to know what the profiler did that made the debug version of my app run so much faster. For one thing, it would be a great convenience to be able to enjoy this speedup while developing; waiting for 2 instead of 20 seconds for my app to start every time I want to check something would be very good for productivity.
I tried my luck with various google searches, and I found a couple of articles on StackOverflow, but none pointed at the exact cause of the problem.
Luckily, after quite a bit of hard thinking, troubleshooting, and browsing through the myriad of potentially relevant settings in Visual Studio, I found the answer:
It is the "Enable unmanaged code debugging" feature.
In Visual Studio this feature is not under "Tools / Options / Debugging", (because that would make too much sense,) it is under "Project / Properties / Debug". Enabling that feature makes everything slow as molasses. The profiler disables the debugger, and that feature with it, so the application appears to run lightning fast.
Here is a StackOverflow question to which I added my newly acquired wisdom:
stackoverflow.com: Launching VS Profiler boosts Application Performance x20?
Here is a StackOverflow question to which I added my newly acquired wisdom:
stackoverflow.com: Launching VS Profiler boosts Application Performance x20?